Nate Tice & Matt Harmon preview the biggest games of Week 5 of the NFL season. The duo start with a massive NFC West showdown featuring the San Francisco 49ers vs. Seattle Seahawks. Nate & Matt break down the red-hot 49ers offense going up against Mike Macdonald’s Seattle defense, our Hoss Fight of the Week.
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Next, the guys deep dive on the Las Vegas Raiders taking on the New England Patriots, including what to expect from an emerging Pats offense. The duo also cover the Buffalo Bills @ Los Angeles Rams: can Matthew Stafford shake off some of his up-and-down play against a lackluster Buffalo defense?
Later, Nate & Matt get into Cheat Sheet, where they each give one key matchup to watch for the Minnesota Vikings @ New Orleans Saints, the (Lamar Jackson-less) Baltimore Ravens @ Atlanta Falcons and the Philadelphia Eagles @ Jacksonville Jaguars in London. The two hosts wrap things up with their Hail Mary bold predictions for the weekend featuring Pittsburgh Steelers WR Roman Wilson and a get-right game for the 0-4 Houston Texans.
(2:35) – 49ers @ Seahawks deep dive
(23:30) – Raiders @ Patriots deep dive
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(41:25) – Bills @ Rams deep dive
(1:05:25) – Cheat Sheet: key matchups to watch
(1:24:55) – Hail Mary bold predictions
PHILADELPHIA, PENNSYLVANIA – OCTOBER 4: Matthew Stafford #9 of the Los Angeles Rams warms up prior to the game against the Philadelphia Eagles at Lincoln Financial Field on October 4, 2026 in Philadelphia, Pennsylvania. The Rams defeated the Eagles 24-20. (Photo by Mitchell Leff/Getty Images)
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