Welcome to Week 10 of the 2026 fantasy football season. We’re at the halfway mark of the campaign and there’s only a few more matchups before your playoffs start. With lineup decisions becoming more and more important, streaming defenses will be key. Here are Justin Boone’s favorite units to stream off the waiver wire.

Ravens vs. Chargers: At 0-8 and the trade deadline looming, Los Angeles is pretty much dead in the water the rest of the season. With the QB room in shambles, the Ravens need to lean on their defense. The Chargers are the best matchup in fantasy for opposing D/ST units, so this is a pretty easy play as far as streamers go.

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Packers vs. Vikings: After struggling a bit to start the year, Green Bay’s unit has really come together, particularly its secondary. The Packers just had four sacks and three INTs against the Patriots on the road, posting 12 fantasy points. Green Bay now has at least eight fantasy points in five of the past six games.

Bills at Jets: Buffalo still has to face Minnesota on MNF in Week 9, but enters that contest coming off 14 fantasy points in Week 8 against the Ravens. New York is down to 2-7 and could move some players before the deadline. This is a great floor play for fantasy managers.